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overview why a prize? prize resources longevity prize homeostatic capacity prize press videos about us advisors faq contact please leave this field empty. overview why a prize? prize resources longevity prize homeostatic capacity prize press videos about us advisors faq contact let’s hack the code! just six decades after orville and wilbur wright launched the aviation age, president kennedy pronounced a moonshot: fly people to the moon and back. eight years later, the mission was accomplished. now, six decades after james watson and francis crick discovered the code of life, it is time to embark on another historic mission: hack the code of life and cure aging. — the (the “prize”) is a $1 million life science competition dedicated to ending aging. ours is one of a growing number of initiatives around the world pursuing this goal—the more shots on goal the better. through an incentive prize, our specific aim is to nurture innovations that end aging by restoring the body’s homeostatic capacity and promoting the extension of a sustained and healthy lifespan. palo alto prize – team approach there are two prizes available and teams may compete for one or both prizes: • a $500,000 homeostatic capacity prize will be awarded to the first team to demonstrate that it can restore homeostatic capacity (using heart rate variability as the surrogate measure) of an aging reference mammal to that of a young adult. • a $500,000 longevity demonstration prize will be awarded to the first team that meets all the requirements of the prize requirements as determined by the judging panel in its sole discretion, including extending the mean lifespan of a wild-type mammalian intervention cohort by 50% relative to acceptable published natural history of untreated norms in a statistically significant (p<.05) manner, using a statistical model (as defined and approved in the official “competition agreement”). the intervention and control cohorts should be age and gender matched and should include an equal number of males and females. if you would like more details on the prize requirements please use the contact form at the bottom of this page . each team participating in the prize is responsible for funding 100% of its participation in the prize including all research and development costs and publishing its work and/or the reproduction of results. to enable a rapid commercial path forward for the innovations, the sponsor of the prize will be contributing an existing pool of relevant intellectual property to the prize effort. palo alto prize – personal stories sign up today! innovation happens in the most magical ways and often it requires people from outside the field of study to see the challenge with a new perspective. if you are ready to sign up as a team to compete – please fill out an intent to participate application if you have any questions or if you would like to review the prize rules, please let us know . let’s do this! “there is a possibility that the timed switch from a functional ans to a dysfunctional ans may be a key underlying mechanism of chronic diseases and aging.” frank longo, m.d. professor and chair, department of neurology and neurological sciences, stanford university “the has the potential to fundamentally impact humankind by unlocking the secrets to longevity and healthy aging.” amir dan rubin president and ceo stanford hospital & clinics “the answers we find with this prize could not only teach us how to enhance lifespan but more importantly brain function and human health in general.” ben barres, m.d., ph.d. chairman, department of neurobiology, stanford university “health extension needs to happen sooner rather than later. i, for one, do not want to be part of the last generation that only lived to an average of 80 years.” sonia arrison author 100 plus, associate founder singularity university “prizes work. they attract the best minds to focus on a breakthrough, media to educate the public and the money necessary to support the innovators.” keith powers managing director, engaged partners “for far too long aging research is undercapitalized and over promoted in non rigorous contexts. its great to finally see an effort to foster cogent science.” laura deming founder, longevity fund “heart rate variability is a powerful potential biomarker. this prize will attract the best and brightest to take on the full puzzle.” nina kjellson managing director, interwest ventures “as a venture investor, i am super excited to meet future teams and the potential opportunities that could result from this prize.” steve herrod managing director, general catalyst partners why a prize? incentive prizes work because they attract: minds prizes attract the best minds to focus on finding solutions to a specific area of innovation. from researchers at universities, to startups, to small teams within larger companies, prizes create a target for innovators to try to solve. prize purses, advanced market commitments, and the glory of winning helps “pull” innovation in a specific direction. by creating a new playing field, prizes also help pull everyone together toward the common goal. media everyone loves a competition and everyone loves heroes, especially the media! when crafted and produced well, incentive prizes are a great way to tell stories and to educate the public about the area of discovery. they also provide a wonderful medium to create heroes out of the hard-working teams that make it happen. money once you have the best minds in the world focusing on a breakthrough area, capital will follow. angel investors, venture capital funds, and the venture arms of corporations are always looking for the next breakthrough area and teams to invest in. prizes help unearth who those teams are, and what they are working on related to the prize, and other products, services and intellectual property that they might have that are not related to the prize. now is the time to launch this prize, because we have reached the point in science, where we really do have the opportunity to solve aging. dr. doris taylor the palo alto prize enables us to attack moonshot problems jin lee give nature the tools and get out of the way doris taylor we have the foundations that will allow us to live to 120 and we can do it. david mendelowitz the race against time is imminent. we need to act now david mendelowitz every moment of our life is a race against time jin lee the longer people live and the more productive they are the more they contribute to society irving zucker we’ve reached a point in science where we really do have the opportunity to solve aging doris taylor you never change things by fighting the existing reality. to change something, build a new model that makes the existing model obsolete. r. buckminster fuller if you keep us in this room long enough, we will solve aging dr. doris taylor give nature the tools and get out of the way. dr. doris taylor we have to reinvent ourselves to make progress irving zucker advisory board victor dzau, m.d. president of the institute of medicine leonard guarente, ph.d. director, glenn laboratory for the science of aging at mit dr. stuart kim, ph.d professor, depts. of developmental biology and genetics stanford university medical center david sinclair, ph.d. professor, genetics dept. harvard medical school john sedivy ph.d. brown faculty, department of molecular biology, cell biology, and biochemistry keith blackwell, m.d, ph.d. principal investigator, the blackwell lab at the joslin diabetes center susan peschin president and ceo alliance for aging research russel j. reiter, ph.d., dr.h.c.mult. professor of cell biology, ut health science center steve jurvetson managing director, draper fisher jurvetson jack hidary founder, hidary foundation frank longo, m.d. professor and chair, department of neurology and neurological sciences, stanford university charles cho, m.d. professor of neurology and neurosurgery, stanford university eric verdin, m.
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